LUMINAD Skin Booster: A Scientific Approach to Skin Longevity and Rejuvenation

LUMINAD is a next-generation injectable skin booster designed to support skin longevity by replenishing Nicotinamide Adenine Dinucleotide (NAD), an essential coenzyme critical for cellular energy metabolism, DNA repair, and activating longevity pathways. Delivered via a precision prefilled syringe, LUMINAD provides a targeted, effective solution for skin revitalization, wrinkle reduction, and long-term skin health maintenance. LUMINAD addresses the root biological causes of aging at the cellular level. This results in enhanced skin elasticity, collagen synthesis, hydration, and protection against environmental damage, positioning it as a leading option in aesthetic medicine for skin rejuvenation, longevity and maintenance.

Scientific Basis and The Role of NAD in Skin Health

NAD is fundamental in cellular functions such as ATP production, mitochondrial metabolism, and DNA repair by poly ADP-ribose polymerase (PARP). Also activates sirtuins (e.g., SIRT1 and SIRT6) (longevity enzymes), proteins that regulate inflammation, promote collagen production, and activate longevity and stress-resistance genes.

NAD levels decline significantly with age, contributing to reduced cellular energy, increased oxidative stress, DNA damage, impaired skin renewal, and reduced cellular repair capacity. By restoring NAD levels, LUMINAD targets the root causes of skin aging at the cellular level, promoting improved skin elasticity, firmness, and resilience while reducing fine lines and pigmentation irregularities, and a youthful appearance through the repair of UV-induced DNA damage and oxidative stress reduction.

Mechanism of Action and Delivery: Injectable vs. Topical NAD

Topical NAD products face major limitations due to poor penetration of NAD molecules through the skin barrier, restricting their effects largely to surface hydration or antioxidative support. In contrast, LUMINAD is administered via superficial or intradermal injection, ensuring nearly 100% bioavailability by delivering NAD directly where cellular regeneration occurs. This precise delivery bypasses enzymatic degradation and skin barriers, leading to rapid cellular uptake and sustained skin benefits including accelerated DNA repair, collagen synthesis, improved skin texture and anti-inflammatory effects, all essential for skin longevity and rejuvenation.

Synergistic Ingredients and Their Role for Multi-Dimensional Skin Benefits

LUMINAD combines NAD with several scientifically supported active ingredients for amplified efficacy:

• Succinic acid: Enhances mitochondrial redox balance and energy production, supporting efficient cell metabolism and repair.

• Hyaluronic acid (HA): Deeply hydrates and plumps the skin, improving barrier function and elasticity.

• Resveratrol: Activates sirtuins and acts as a potent antioxidant, amplifying NAD’s anti-aging effects, enhances DNA repair

• Amino acids: Provide building blocks for collagen synthesis and stimulate tissue repair.

• Acetyl Hexapeptide-8: “Botox-like peptides” that reduce expression lines, smooth out dynamic wrinkles and improve firmness, encourage a more relaxed and youthful appearance

• Niacinamide (Vitamin B3): Boosts cellular NAD level, reduces inflammation, and strengthens the skin barrier.

• Tranexamic acid: Reduces hyperpigmentation and promotes an even skin tone.

• Trehalose & Escin: Stabilize NAD and reduce inflammation, improve microcirculation, and support skin hydration.

• Ascorbyl glucoside (Vitamin C derivative): A stable Vitamin C derivative promoting antioxidant protection, collagen stimulation, and brightening.

• Panthenol (Vitamin B5): Hydrates, supports lipid production, and aids skin repair and soothing.

The synergy among these ingredients targets various aging mechanisms, from energy metabolism to pigmentation control and barrier integrity, improve texture, elasticity, hydration, radiance, and ensure comprehensive skin rejuvenation.

Clinical Efficacy and Safety Profile

Clinical studies indicate that LUMINAD increases skin elasticity by as much as 23% within 12 weeks, alongside visible reductions in fine lines and improvements in skin brightness and hydration. The product stimulates collagen and elastin synthesis, accelerates DNA repair, reduces oxidative damage from environmental stressors such as UV radiation and strengthens the skin barrier. Well tolerated among patients, side effects are minimal and mostly restricted to transient mild discomfort at the injection site, with rare systemic effects such as mild headaches or fatigue reported. The steady absorption profile reduces the risk of adverse effects commonly seen with intravenous NAD administrations, making LUMINAD safer and more convenient for routine use.

Compared to IV NAD infusion, which delivers rapid systemic NAD but often causes side effects like flushing and requires lengthy clinical visits, LUMINAD offers sustained localized delivery with better patient comfort and convenience. Topical NAD products fail to deliver NAD effectively into the skin’s deeper layers, limiting their benefits primarily to surface effects. The targeted, gradual release of NAD in LUMINAD enhances patient comfort, reduces side effects, improves compliance, and provides superior anti-aging benefits for skin health.

Recommended Treatment Protocol

LUMINAD is indicated for skin revitalization, anti-aging maintenance, and post-procedure recovery on the face, neck, décolleté, and hands. Typical protocols involve an initial phase of 3-4 sessions spaced 3-4 weeks apart, followed by maintenance treatments every 6 months depending on the patient’s skin condition and goals. It can be combined with microneedling, lasers, radiofrequency, platelet-rich plasma, or dermal fillers for synergistic enhancement of clinical results.

Broader Role of NAD in Anti-Aging and Skin Longevity

Beyond skin-related benefits, NAD is pivotal in systemic anti-aging due to its regulation of cellular senescence, energy metabolism, and DNA maintenance. By preserving mitochondrial health and activating protective sirtuins, NAD delays the biological aging process fundamentally. The use of LUMINAD aligns with emerging regenerative aesthetic medicine approaches focusing on skin longevity by preserving the molecular and cellular integrity critical for youthful skin.

Conclusion

LUMINAD represents an innovative advance in aesthetic medicine by integrating cutting-edge NAD science with a synergistic blend of bioactive compounds. By addressing the biological root causes of skin aging, LUMINAD provides a comprehensive, safe, and effective solution for skin longevity, rejuvenation, and radiant youthfulness.